In the area of human disease testing, current methods are expensive to perform, take a long time, they require the patient to move; they are not suitable for emergency departments or people with chronic illnesses. Therefore, the use of biosensors in point-of-care (POC) testing devices has attracted considerable attention in the past few years, mainly because of their high specificity, portability, and relatively low cost. Coupling these devices with miniaturized electrochemical transducers has shown great potential toward simple, rapid, and cost-effective analysis that can be performed in the field, especially for healthcare diagnostics.