This work demonstrated an ingenious combination of the catalytic hairpin assembly and enzymatic signal amplification for highly sensitive and specific quantitative determination of piR–651 as a novel cancer biomarker.
Read MoreResearch Scientist in Chemistry
In the area of human disease testing, current methods are expensive to perform, take a long time, they require the patient to move; they are not suitable for emergency departments or people with chronic illnesses. Therefore, the use of biosensors in point-of-care (POC) testing devices has attracted considerable attention in the past few years, mainly because of their high specificity, portability, and relatively low cost. Coupling these devices with miniaturized electrochemical transducers has shown great potential toward simple, rapid, and cost-effective analysis that can be performed in the field, especially for healthcare diagnostics.
This work demonstrated an ingenious combination of the catalytic hairpin assembly and enzymatic signal amplification for highly sensitive and specific quantitative determination of piR–651 as a novel cancer biomarker.
Read MoreAn impedance-based DNA multiplexed biosensor was designed to simultaneously detect Escherichia coli (yaiO gene) and its virulent f17 variant.
Read MoreThis work describes a new biosensor to sensitively determine the levels miRNAs via dual signal readout involving competitive hybridization.
Read MoreReliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers.
Read MoreThis book chapter presents a general summary of miRNA biogenesis, their link to cancer, and biological methods for their detection. Thanks to their ease of use and high sensitivity, electrochemical and optical techniques were used to detect miRNAs with or without the assistance of amplification methods.
Read MoreThis work reports the design of a magnetofluorescent bioplatform for the direct and specific detection of the viral RNA of SARS-CoV-2
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