Riham Zayani, PhD

Research Scientist in Chemistry

Riham Zayani, PhD
Research Scientist | Biosensors | POC diagnostics

ABOUT ME:

I am a research scientist with skills and experience in chemistry, biotechnology and biological sciences. My expertise lies in the development and design of novel electrochemical and optical (nano)biosensing platforms for innovative point-of-care diagnostics.

Driven by my passion for translating research into practical applications by commercializing exciting innovation in biotechnology to develop biosensing systems that can address today's diagnostic challenges.

I am open to exploring exciting positions at the crossroads of research and industry, with a focus on biotech/biopharma companies. Aiming to leverage expertise in biosensor development, analytical chemistry, and molecular biology to drive commercialization and innovative research endeavors.

Thank you for reviewing my page and if you find I am a qualified candidate, or have opportunities you can offer please do not hesitate to connect with me or reach me out at: riham.zayani@fst.utm.tn

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Development of rapid test platforms for medical diagnostics

Biosensors for Point-of-care diagnostics

Biosensors for Point-of-care diagnostics

In the area of human disease testing, current methods are expensive to perform, take a long time, they require the patient to move; they are not suitable for emergency departments or people with chronic illnesses. Therefore, the use of biosensors in point-of-care (POC) testing devices has attracted considerable attention in the past few years, mainly because of their high specificity, portability, and relatively low cost. Coupling these devices with miniaturized electrochemical transducers has shown great potential toward simple, rapid, and cost-effective analysis that can be performed in the field, especially for healthcare diagnostics.

This work demonstrated an ingenious combination of the catalytic hairpin assembly and enzymatic signal amplification for highly sensitive and specific quantitative determination of piR–651 as a novel cancer biomarker.

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An impedance-based DNA multiplexed biosensor was designed to simultaneously detect Escherichia coli (yaiO gene) and its virulent f17 variant.

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This work describes a new biosensor to sensitively determine the levels miRNAs via dual signal readout involving competitive hybridization.

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Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers.

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This book chapter presents a general summary of miRNA biogenesis, their link to cancer, and biological methods for their detection. Thanks to their ease of use and high sensitivity, electrochemical and optical techniques were used to detect miRNAs with or without the assistance of amplification methods.

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This work reports the design of a magnetofluorescent bioplatform for the direct and specific detection of the viral RNA of SARS-CoV-2

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